In the world of medical science, breakthroughs are happening every moment. Almost every ailment in the world now has a cure, giving afflicted patients all around the world a hope to live the life as they would want it.
The technique of drug invention and testing is a long, tedious and expensive one. Scientists, researchers and pharmacologists work relentlessly to invent that drug which would act as an elixir for an ailment. In the same way, the drug has to go through a number of processes to ensure that the drug passes through all the quality requirements.
High Content Analysis or visual screening is the process used in biochemical, biological and drug discovery for the identification of small molecules and peptides and RNA of a cell in a way which is desired.
The process is also known as High Content Screening and is like a phenotypic screen for cell where the various changes in the cell, which will ultimately affect the structure and functioning of the drug is observed. There are various changes which take place in the cell including morphological changes where the shape and size of the cell changes rapidly. In order to see that the cell is functioning in the best possible way, and the drug will have an effect on that cell, the screening is beneficial.
The cells which are involved in this procedure are subjected to various parameters and the changes are obtained then. For instance, if the effect of a drug on a particular cell has to be studied, the cell will be first incubated with the substance and then the various changes would be analyzed over a period of time.
There are various advantages associated with this process, the first and foremost being the discovery of novel drugs which can cure a large number of ailments. Assay Optimization which involves testing the drugs in a controlled environment often becomes a difficulty and is several times a bottleneck in the process of testing. But the use of robots and robotic handling procedures have helped to simplify and reduce the time required for the testing and screening of the process.
Automated Assay Optimization has helped to make the job a great success. The job of drug testing and discovery has been simplified and the process gets done in a much faster way. Last, but not the least, the targeted work has been improved manifold from the migration of manual to automated work.
SLAS is an worldwide community of individual scientists, researchers and providing High Content Screening or Analysis. High Content Analysis is the process used in biochemical, biological and drug discovery for the identification of small molecules.
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